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Description

P.et al (1994)

LPS could activate airway epithelial cells, neutrophils, and alveolar macrophages, resulting in the release of numerous inflammatory mediators, such as reactive oxygen species (ROS), tumor necrosis factor- (TNF-), and interleukin-6 (IL-6)

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The honest clinical picture is cautious: DSIP is investigational and research-only , much of the existing human data is older, limited, and inconsistent , and the available trials point in conflicting directions